Sharad Kumar Yadav
Veterinary University, India
Title: Nanomaterials for novel vaccine development in animal sciences
Biography
Biography: Sharad Kumar Yadav
Abstract
Vaccines in the current scenario of a research play particular role in prophylactic, therapeutic agents in cancer, disease and different types of the infections. Synthetic nanoparticles now a day are playing a significant role in vaccines designs and development because these synthetic nanoparticles based vaccines show greater safety, efficacy, and longevity over the previously used vaccines. Nanocarriers with various biotechnological properties and structures have been used vastly both in vitro and in vivo drug and gene delivery. The groups of nanocarriers have been polymeric nanoparticles, lipid-based carriers (liposome, micelle, dendrimers, carbon nanotubes, and gold nanoparticles are some of the members of the lipid-based nanocarriers and these polymeric nanoparticles delivery system have huge properties which include these easily biodegradable, biocompatible, inexpensive, no-immunogenic, non-toxic, water soluble and most importantly easy to be synthesized. However, some obstacles still remain due to lack of real/fundamental knowledge on the detail molecular mechanism of work and in vivo bioeffects of these nanoparticles. These basic facts of the in vivo biodistribution and fate of nanoparticles will ultimately extra gate design of the new nanoparticles comprising the vaccines for the future. This keynote address is a broad overview of the current scenario in nanoparticle in vaccinology and modern vaccine development.